
On 10 October 2021, René Rast announced he would be unable to return for the 2022 Formula E season as he returned to the DTM series instead, citing the commitment requirement for DTM.On 15 September 2021, former Audi Sport driver Lucas di Grassi announced his signing for Venturi Racing, replacing Norman Nato and joining Edoardo Mortara.
On 2 September 2021, Maximilian Günther announced his switch from Andretti Autosport to Nissan e.dams. On 23 June 2021, Oliver Rowland announced his switch from Nissan e.dams to Mahindra Racing. On 2 November 2021, Jaguar Racing announced that the team would be rebranded as Jaguar TCS Racing for the 2021–22 season as a result of a title sponsorship deal with Tata Consultancy Services. On 1 November 2021, Envision Virgin Racing announced that the team would be rebranded as Envision Racing for the 2021–22 season as the Envision Group had taken complete ownership of the race team. On 18 August 2021, Mercedes-Benz announced that this would be their last season in Formula E. However, they remained in the sport as a powertrain supplier for the 2021–22 season as Andretti Autosport, having been in a partnership with them. As announced on 2 December 2020, BMW have left Formula E at the end of the 2020–21 season. However, Audi remained in the sport until the end of the 2021–22 season as powertrain supplier for Envision Racing. As announced on 30 November 2020, Audi Sport and their team Abt Sportsline have left Formula E at the end of the 2020–21 season. All teams used a spec Spark SRT05e chassis and Michelin tyres.